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学术讲座【Atomic cryoEM for proteins, nucleic acids and lipids】

时间:2018-01-04浏览:574设置

时间201818日上午9:30-10:30

地点:理工楼11号楼103会议室

主讲Dr. Z. H. Zhou, UCLA

主办:生命科学学院

专家简介:Dr. Z. H. Zhou is a Professor of Microbiology, Immunology and Molecular Genetics and the Founding Director of the Electron Imaging Center for Nanomachines at University of California, Los Angeles (UCLA). He received his early education in physics at the University of Science and Technology of China before earning his PhD (in 1995) in biochemistry at the Baylor College of Medicine, in Houston, Texas, USA, under the supervision of cryo electron microscopy (cryoEM) pioneer Wah Chiu. From 1995-1999, he carried out his postdoctoral training in computer science and applied mathematics under Prof. L. Ridgway Scott and developed high-performance image processing software for cryoEM reconstruction.

Zhou has published about 200 research articles and book chapters, many in leading journals like Nature, Science and Cell. He uses cryoEM to determine three-dimensional structures of molecular complexes near their native functional states at molecular to atomic resolutions. In 2008, his group was the first to demonstrate near atomic resolution cryoEM by single-particle analysis in a milestone Nature paper documenting the first atomic model of the cytoplasmic polyhedrosis virus. Broadly, his research addresses fundamental questions, such as how proteins and nucleic acids interact to store and release energy, to transduce signals, and to perform tasks of chemistry underlying reproduction.

Zhou was a Pew Scholar in Biological Sciences and a Basil O’Connor Scholar of the March of Dimes Foundation. He is a recipient of Burton Award and K. H. Kuo Distinguished Scientist Award.


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